Head-To-Head Survey: Prosensa (RNA) & Sunesis Pharmaceuticals (SNSS)

Prosensa (NASDAQ: RNA) and Sunesis Pharmaceuticals (NASDAQ:SNSS) are both small-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, earnings, valuation, risk, analyst recommendations, profitability and institutional ownership.


This table compares Prosensa and Sunesis Pharmaceuticals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Prosensa N/A -72.90% -57.94%
Sunesis Pharmaceuticals N/A N/A -140.22%

Analyst Ratings

This is a summary of current ratings and price targets for Prosensa and Sunesis Pharmaceuticals, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prosensa 0 0 0 0 N/A
Sunesis Pharmaceuticals 0 2 2 0 2.50

Sunesis Pharmaceuticals has a consensus target price of $4.49, indicating a potential upside of 10.40%. Given Sunesis Pharmaceuticals’ higher probable upside, analysts plainly believe Sunesis Pharmaceuticals is more favorable than Prosensa.

Earnings & Valuation

This table compares Prosensa and Sunesis Pharmaceuticals’ top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Prosensa N/A N/A N/A ($0.50) -37.30
Sunesis Pharmaceuticals $670,000.00 208.06 -$35.46 million ($1.52) -2.68

Prosensa has higher earnings, but lower revenue than Sunesis Pharmaceuticals. Prosensa is trading at a lower price-to-earnings ratio than Sunesis Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Institutional & Insider Ownership

53.2% of Sunesis Pharmaceuticals shares are held by institutional investors. 10.2% of Sunesis Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.


Sunesis Pharmaceuticals beats Prosensa on 7 of the 9 factors compared between the two stocks.

About Prosensa

Prosensa Holding N.V., formerly Prosensa Holding B.V., is a biotechnology company engaged in the discovery and development of ribonucleic acid-modulating (RNA)-modulating, therapeutics for the treatment of genetic disorders. The Company’s primary focus is on rare neuromuscular and neurodegenerative disorders with a large unmet medical need, including Duchenne muscular dystrophy, myotonic dystrophy and Huntington’s disease. The Company’s clinical portfolio of RNA-based product candidates is focused on the treatment of Duchenne muscular dystrophy (DMD). The Company’s platform technology allows the development of RNA-modulating therapeutics that either interferes with splicing (exon skipping, exon inclusion, or splice mutation correction), remove mutant RNA, or block RNA expression, for different indications.

About Sunesis Pharmaceuticals

Sunesis Pharmaceuticals, Inc. is a biopharmaceutical company. The Company focuses on the development and commercialization of its pipeline of oncology therapeutics for the treatment of solid and hematologic cancers. The Company offers QINPREZO (vosaroxin), which is a product candidate for the treatment of acute myeloid leukemia (AML). Vosaroxin is an anticancer quinolone derivative (AQD). The Company’s other kinase inhibitor pipeline include TAK-580, SNS-062 and SNS-229. TAK-580 is an oral, investigative drug selective for pan-Raf kinase inhibition, in patients with relapsed or refractory solid tumors. SNS-062 is a non-covalently binding inhibitor of Bruton’s tyrosine kinase (BTK). The Company has completed the pre-clinical studies for SNS-062. SNS-229 and SNS-510 are two PDK1 inhibitors. PDK1 is a kinase and mediator of Phosphoinositide 3-kinase/AKT (PI3K/AKT) signaling, which is a pathway involved in cell growth, differentiation, survival and migration.

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