Comparing Juno Therapeutics (JUNO) & Shire-Nps Pharmaceuticals (NPSP)

Juno Therapeutics (NASDAQ: JUNO) and Shire-Nps Pharmaceuticals (NASDAQ:NPSP) are both mid-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their institutional ownership, risk, valuation, analyst recommendations, dividends, earnings and profitability.

Earnings & Valuation

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This table compares Juno Therapeutics and Shire-Nps Pharmaceuticals’ top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Juno Therapeutics $111.87 million 90.26 -$245.58 million ($5.38) -16.16
Shire-Nps Pharmaceuticals N/A N/A N/A ($0.08) N/A

Shire-Nps Pharmaceuticals has lower revenue, but higher earnings than Juno Therapeutics. Juno Therapeutics is trading at a lower price-to-earnings ratio than Shire-Nps Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.


This table compares Juno Therapeutics and Shire-Nps Pharmaceuticals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Juno Therapeutics -390.66% -39.24% -29.31%
Shire-Nps Pharmaceuticals -2.96% -5.98% -2.77%

Institutional and Insider Ownership

70.2% of Juno Therapeutics shares are held by institutional investors. 15.1% of Juno Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Analyst Ratings

This is a summary of current ratings and recommmendations for Juno Therapeutics and Shire-Nps Pharmaceuticals, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Juno Therapeutics 0 15 2 0 2.12
Shire-Nps Pharmaceuticals 0 0 0 0 N/A

Juno Therapeutics currently has a consensus price target of $56.21, indicating a potential downside of 35.36%.

About Juno Therapeutics

Juno Therapeutics, Inc. (Juno) is a biopharmaceutical company, which is focused on developing cellular immunotherapies for the treatment of cancer. The Company is developing cell-based cancer immunotherapies based on its chimeric antigen receptor (CAR) and T cell receptor (TCR) technologies to genetically engineer T cells to recognize and kill cancer cells. Its product candidates JCAR017, JCAR014, and JCAR015, as well as an additional early stage product candidate incorporating a fully human binding domain, leverage CAR technology to target CD19, a protein expressed on the surface of almost all B cell leukemias and lymphomas. Its CAR product candidate JCAR018 targets CD22, a different protein commonly expressed on the surface of B cell leukemias and lymphomas. Its MUC-16 directed product candidate is an armored CAR that secretes the cytokine interleukin 12 (IL-12), which may help to overcome the inhibitory effects that the tumor microenvironment can have on T cell activity.

About Shire-Nps Pharmaceuticals

NPS Pharmaceuticals, Inc. (NPS) is a biopharmaceutical company focused on delivering therapies that transform the lives of patients with rare diseases. The Company’s primary product Gattex 0.05 mg/kg/d (teduglutide [rDNA origin]) for injection, for subcutaneous use was approved the United States Food and Drug Administration (FDA) for the treatment of adult patients with short bowel syndrome (SBS) who are dependent on parenteral support. The Company’s second principal product, Natpara (recombinant human parathyroid hormone 1-84 [rDNA origin] injection, has been developed for hypoparathyroidism, a rare multidimensional disorder characterized by deficient or absent parathyroid hormone (PTH). The Company has collaborations or royalty agreements with Amgen, Janssen, GlaxoSmithKline and Kyowa Hakko Kirin.

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